Join Us in Fighting Chronic Kidney Disease Caused by Variations in the APOL1 Genotype

If you have been diagnosed with kidney disease, have symptoms of kidney disease, or a family history of kidney disease, this clinical research study may be an option for you. Vertex Pharmaceuticals is researching how many people with chronic kidney disease (CKD) that is not caused by diabetes have a genetic variation in the apolipoprotein L1 (APOL1) gene. APOL1 is a naturally occurring gene that can be found in many tissues of the body, including the blood, saliva, and kidneys. People with CKD not caused by diabetes who have a mutation in their APOL1 gene have a higher risk of losing kidney function.

See if you may qualify

We are currently enrolling people between the ages of 12 and 60 years old who have a history of increased protein levels in their urine and do not have diabetes. If you are interested in taking part in this research study, please continue below and complete the questionnaire to determine if you are a good candidate and eligible for the study.

See If You May Qualify

Step 1 of 3

By answering the following prescreening questions, you agree to provide your information to Praxis, a service provider of the sponsor of this study, Vertex Pharmaceuticals Incorporated (Vertex). The categories of information collected via this questionnaire include: your name and contact information, information about your health and lifestyle, and any other information that you provide. Your information will be used only to determine whether you are eligible for this research study and, if you consent, to inform you of potential Vertex research studies in the future. It will not be shared with Vertex. If your answers to the questionnaire indicate you may be eligible for the study and you elect to share your contact information, Praxis (we) will share your information with Circuit Clinical, who is also a service provider to Vertex on this study, and who will contact you to do a full screening. Based on the results of that screening, and with your permission, your information would be shared with a research site. We will not share your personal information with anyone outside of this study other than as required by law, and we will not sell personal information collected from you as part of this study screening.

For a fuller description of Vertex’s privacy practices, and of your privacy rights if you are a California resident, please see Vertex’s privacy policy.

If you have a question or want to exercise your privacy rights detailed in the above privacy policy, please contact Praxis at, as Vertex will not receive your identifiable information.

We need this information to see which research site is closest to you.

e.g., 12345


This website uses Secure Socket Layer technology and encryption methods to protect personal health information. If you’d like to know more about our privacy policy, click here.