Researchers are conducting a clinical research study to find out how many people with chronic kidney disease (CKD) have a genetic form of the disease caused by a change in a gene called the apolipoprotein L1, or APOL1, gene. Current treatments for CKD caused by variations in the APOL1 gene do not treat the genetic cause of this disease, and even with these treatments, people who have APOL1 genetic variations often end up having kidney failure.
This clinical research study will require a single study visit where blood and saliva samples will be collected to determine if participants have changes in the APOL1 gene. This can be done at a study site or in your home. If you choose to participate, the results of this investigational genetic test may qualify you for a future clinical research study where researchers will be testing an investigational medication that may help treat people with CKD caused by changes in the APOL1 gene.
To learn more about the blood and saliva sample collection, DNA (genetic) testing, and genotyping that will take place as part of this study, please watch the video.